The incidence, subtypes and demographics of patients with Germ Cell Tumours at Universitas Paediatric Oncology Services from 2000 to 2021
| dc.contributor.advisor | du Plessis, J. | en_ZA |
| dc.contributor.author | Thottekkat, Krishna | en_ZA |
| dc.date.accessioned | 2025-01-03T12:26:01Z | |
| dc.date.available | 2025-01-03T12:26:01Z | |
| dc.date.issued | 2023 | en_ZA |
| dc.description | Dissertation (M.Med.(Paediatrics and Child Health))--University of the Free State, 2023 | en_ZA |
| dc.description.abstract | Extracranial Germ Cell Tumours (EGCTs) are a recognised rare oncological entity and most of the information available comes from the developed world. There is a paucity of information regarding these tumours (especially from a Paediatric Oncology standpoint) in South Africa and the world. This research endeavours to describe the incidence, subtypes and demographics of patients with EGCTs in the Free State and associated drainage areas and see how it compares to available published data on the matter. To achieve this, a retrospective descriptive study approach was adopted, and data was collected from patients who have attended the Paediatric Oncology Unit at Universitas Academic Hospital in the last 21 years. The research outputs are firstly to describe the incidence, subtypes, demographics, treatment modalities and mortality of patients with GCTs who have presented to the Universitas Paediatric Oncology Services from 2000 until 2021. Secondly, to compare our findings with other South African studies, studies from other parts of Africa, Asia, and developed regions. The impact of this study does not lie solely in the information it provides but in the possible questions, it will raise. With the careful and studied analyses of the available data, this research can provide information that can be used as a platform on which to build further research questions to better clinical practice. Without adequate data collection and analyses in the current South African setting, the South African population is incumbent on the use of data collected in dissimilar populations and with different challenges. By filling this niche, we can better direct future research, focus and resources, for the benefit of this studied population. | en_ZA |
| dc.identifier.uri | http://hdl.handle.net/11660/12905 | |
| dc.language.iso | en | |
| dc.publisher | University of the Free State | en_ZA |
| dc.rights.holder | University of the Free State | en_ZA |
| dc.subject | Extracranial Germ Cell Tumours | en_ZA |
| dc.subject | Paediatric cancers | en_ZA |
| dc.subject | Age standardised rate | en_ZA |
| dc.subject | Histological subtypes | en_ZA |
| dc.subject | Demographics | en_ZA |
| dc.subject | Treatment | en_ZA |
| dc.subject | Mortality | en_ZA |
| dc.subject | Free State | en_ZA |
| dc.subject | South Africa | en_ZA |
| dc.title | The incidence, subtypes and demographics of patients with Germ Cell Tumours at Universitas Paediatric Oncology Services from 2000 to 2021 | en_ZA |
| dc.type | Dissertation |