South African fish poisonous plants VI. Isolation and study of Saponins from Neorautanenia edulis C.A. SM.

dc.contributor.advisorGroenewoud, P.
dc.contributor.authorLabuschagne, Willem Adriaan
dc.date.accessioned2020-11-18T13:51:22Z
dc.date.available2020-11-18T13:51:22Z
dc.date.issued1955
dc.descriptionDissertation (M.Sc.(Chemistry))--University of the Free State, 1955
dc.description.abstractThe object of the present investigation was to extract and isolate the fish-toxic saponin present in the tuber and the aerial portions of Neorautanenia Edulis C.A. Sm. Various methods of extraction were attempted, and the best found to be that with hot 95% ethyl alcohol. Regarding the isolation of the saponin, it was found that the etherate formation with the alcoholic extract, proved to be the most satisfying. Various other methods were also tried, but none of them gave a fish-toxic saponin. Toxicity tests on fish were carried out, and the most toxic compound found to be that from the etherate formation, mentioned above. The toxic compounds were further purified by extraction with ethyl alcohol, extracting the saponin and leaving an insoluble material which was identified as cane sugar. Various methods of hydrolysis were attempted, but the saponin was resinified by the concentrated hydrochloric acid. The purest form of the toxic saponin obtained had a yellow syrupy nature. It was very toxic, to fish, but could not be hydrolised in order to identify it.en_ZA
dc.identifier.urihttp://hdl.handle.net/11660/10662
dc.language.isoenen_ZA
dc.publisherUniversity of the Free Stateen_ZA
dc.rights.holderUniversity of the Free Stateen_ZA
dc.subjectBotanical chemistryen_ZA
dc.subjectNeorautanenia edulisen_ZA
dc.subjectPoisonous plantsen_ZA
dc.titleSouth African fish poisonous plants VI. Isolation and study of Saponins from Neorautanenia edulis C.A. SM.en_ZA
dc.typeDissertationen_ZA
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