Coarctation of the Aorta: a 10-year follow-up study of patients treated at the Department of Peadiatric Cardiology, Universitas Academic Hospital

Master’s Dissertation

Abstract

English
Background: Coarctation of the aorta accounts for 6-8% of all congenital cardiac lesions. It can be treated surgically or percutaneously depending on the age and weight at presentation and associated cardiac lesions. Objectives: To describe the outcomes of management in patients with native coarctation of aorta with regard to re-intervention and mortality rate. Methods: A retrospective, descriptive review of patients with native coarctation of aorta was done at Universitas Academic Hospital using an electronic database. Included were patients who presented from 01 Jan 2007 – 31 Dec 2016, from birth to 19yrs. Results: The study comprised of 107 patients, median age of 33 days (1 – 4940) with a median weight of 3.9kg (1 – 53.5kg).Common associated cardiac lesions included PDA (n=61; 57%), bicuspid valves (n=41; 38.3%) and VSD (n=31; 29%). A total of 82 patients (75.7%) required an intervention in which 71(86.6%) had surgery with 12(14.6%) requiring a second intervention, while 11(13.6%) had percutaneous procedures with 7(63.6%) requiring a second intervention. Overall mortality was 17(15.9%), the cause of death in 14(82.4%) was cardiac related. Conclusion: From the results of this review surgery remains the preferred treatment for coarctation of the aorta and are associated with a lower recoarctation rate compared to percutaneous interventions.

Keywords

English
Hypertension Restenosis End-to-end anastomosis Angioplasty Balloon-dilatation Turner Syndrome Cardiac failure Aortic coarctation Stents (Surgery)
Record information

Authors

Nyindi, Nompi Margaret

Publisher

University of the Free State
Advisors
Buys, D.
Brown, S.

Description

Dissertation (M.Med (Paediatrics and Child Health))--University of the Free State, 2019