Normal platelet count in the HIV positive pregnant patient
Loading...
Date
2019-04
Authors
Van Wyngaard, Bianca
Journal Title
Journal ISSN
Volume Title
Publisher
University of the Free State
Abstract
Background. Thrombocytopenia complicates 6.6% – 11.6% of all pregnancies. Gestational Thrombocytopenia accounts for the majority of cases, it is usually mild with spontaneous resolution postpartum. It is estimated that more than 25% of pregnant South African patients are HIV positive. Objectives. The objective of the study was to determine the platelet count for HIV positive pregnant patients. This will lead to minimizing unnecessary invasive testing and workup for other pathologies. Method. This was a prospective descriptive study in which low and mild risk pregnant patients with WHO stage 1 HIV disease were recruited for participation. In patients that needed routine blood tests drawn, a platelet count was added. Patients were either first visit patients or following up for routine antenatal care. Results. For all participants (n = 120), the mean platelet count was 270.9 x 10 ⁹/L (range 91 –488). For first trimester participants (n = 37), the mean platelet count was 282.3 x 10 ⁹/L (range 103 – 441). For the second trimester participants (n = 28), the mean platelet count was 263.7 x 10 ⁹/L (range 91 - 470). For the third trimester participants (n = 34), the mean platelet count was 260.2 x 10 ⁹/L (range 99 - 488). For the participants where no trimester was indicated (n = 21), the mean platelet count was 278.1 x 10 ⁹ /L (range 181 - 426). Discussion and Conclusion. Stage 1 HIV does not have a clinical significant impact on the platelet count in pregnant patients.
Description
Keywords
Dissertation (M.Med. (Obstetrics and Gynaecology))--University of the Free State, 2019, Thrombocytopenia, Pregnancy, HIV, Platelet, Thrombocytopenia -- Pregnancy, Thrombocytopenia -- HIV and AIDS, Low platelet count