A comparison of Balsol versus Ringers Lactate as cell saver washing solutions for packed red blood cells as part of priming solution in paediatric elective Cardiac Surgery with Cardio Pulmonary Bypass
| dc.contributor.advisor | Van Aswegen, A. | |
| dc.contributor.author | Swanepoel, M. | |
| dc.date.accessioned | 2019-07-10T06:16:02Z | |
| dc.date.available | 2019-07-10T06:16:02Z | |
| dc.date.issued | 2018-08 | |
| dc.description.abstract | Introduction: The need to add Packed Red blood cells (PRBC) to the Cardio Pulmonary Bypass (CPB) circuit prime cause unphysiological acid-base, electrolyte and metabolite values. The main reason why filtering techniques are used prior to paediatric cardiac bypass are to prepare a nearly physiological priming solution. It has become standard practice to wash PRBC before adding it to neonate CPB. Aim: The aim was to measure and compare pH, electrolytes, metabolites, Haematocrit and Haemoglobin of packed RBC, washed with either Balsol or Ringers Lactate. Methodology: A series of 20 units of packed RBC’s was used and randomised to a Balsol group (control group) and a Ringers lactate group (interventional group) according to a randomisation list. A blood sample was obtained pre and post wash and analysed. Results: In both groups there was a significant decrease in Potassium (K+), Sodium (Na+), Glucose, Haematocrit and Haemoglobin. In the Ringers Lactate group there was a significant increase in Partial pressure of Oxygen (pO2) and Calcium (Ca2+). In the Balsol group there was a significant increase in pH. There was a statistically significant difference in the percentage change between the two groups for pH, Partial pressure of Carbon dioxide (pCO2), pO2, Ca2+ and Lactate. Conclusion: The pCO2, pO2, Ca2+, Lactate and Bicarbonate (HCO3-) is closer to physiological values in the Ringers Lactate group and the pH, K+ and Cl- is closer to physiological values in the Balsol group. Glucose, Na+, Hct and Hb changed to the same extend in both groups. | en_ZA |
| dc.identifier.uri | http://hdl.handle.net/11660/9998 | |
| dc.language.iso | en | en_ZA |
| dc.publisher | University of the Free State | en_ZA |
| dc.rights.holder | University of the Free State | en_ZA |
| dc.subject | Dissertation (M.Med. (Anaesthesiology))--Univesity of the Free State, 2018 | en_ZA |
| dc.subject | Paediatric cardiac bypass | en_ZA |
| dc.subject | Filtering techniques | en_ZA |
| dc.title | A comparison of Balsol versus Ringers Lactate as cell saver washing solutions for packed red blood cells as part of priming solution in paediatric elective Cardiac Surgery with Cardio Pulmonary Bypass | en_ZA |
| dc.type | Dissertation | en_ZA |