Masters Degrees (Paediatrics and Child Health)
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The association between serum procalcitonin levels and outcomes of patients admitted to two tertiary paediatric intensive care units in the Bloemfontein academic complex: a retrospective analytical study
(University of the Free State, 2021-01)Background: The risk of mortality should be assessed in all patients admitted to the Paediatric Intensive Care Unit (PICU). Procalcitonin (PCT) is a valuable biomarker in the diagnosis of sepsis in the PICU. Its use as a ... -
The incidence, clinical profile and antimicrobial susceptibility pattern of Acinetobacter baumannii sepsis in premature neonates at Universitas Academic Hospital for the period 1 January 2016 to 31 December 2018, a retrospective descriptive study
(University of the Free State, 2021-02)BACKGROUND: Acinetobacter baumannii is an emerging and challenging pathogen in neonatal units, due to its ability to develop resistance against antibiotics. Studies on Acinetobacter baumannii infection in premature neonates ... -
Characteristics and outcomes of infants with cytomegalovirus infection in Bloemfontein
(University of the Free State, 2020-09)Background: Cytomegalovirus (CMV) can be transmitted from mother to child and can be congenital or postnatally acquired. Emerging evidence has shown that CMV and other congenital and neonatal infections, are under-appreciated ... -
Prevalence of thrombocytopaenia in neonates admitted in neonatal high care unit of Pelonomi Tertiary Hospital Bloemfontein between January 2017 and June 2017
(University of the Free State, 2019-08)BACKGROUND: Thrombocytopaenia is the most common haematological abnormality, besides anaemia, found in the neonates admitted to a neonatal intensive care unit. Even though most cases are mild or moderate, requiring minimal ... -
Screening, diagnosis and management of autism spectrum disorders amongst healthcare practitioners in South Africa
(University of the Free State, 2021-05)Background: There is a global increase in Autism spectrum disorders (ASD) prevalence, awareness and its effect on the burden of disease. It is crucial that ASD is recognized and diagnosed timeously for early intervention ... -
Association between Hypochromic Microcytic Anaemia and Febrile Seizure in patients admitted at Pelonomi Tertiary Hospital in Bloemfontein from January 2019 to December 2019
(University of the Free State, 2021-07)BACKGROUND: Febrile seizure, which affects 2-5% of neurologically healthy children, is the most common type of seizure in children. The seizures occur in the context of a global iron deficiency that stands out as the most ... -
Clinical presentation and outcomes of anomalous left coronary artery from the pulmonary artery: a retrospective study from January 1998 - August 2019 at the Department of Paediatrics Cardiology, Universitas Hospital
(University of the Free State, 2020-09)BACKGROUND: Anomalous left coronary artery from the pulmonary artery (ALCAPA) or Bland-White-Garland syndrome is a rare congenital anomaly that has profound effects on heart function. Patients with ALCAPA present with ... -
PIM 3 predicted mortality compared to the observed mortality rate for patients in the PICU in Universitas Academic Hospital, segregated into four physico-chemical aspects for acid-base disturbances
(University of the Free State, 2020-07)Background: The PIM 3 score is widely used in PICU’s, to monitor the quality of care of patients. The reason for this study is to compare the mortality rate for the PICU at Universitas Academic Hospital with the PIM 3 ... -
Blood culture contamination in the Department of Paediatrics of Universitas- and Pelonomi Hospitals
(University of the Free State, 2020-08)Background: Sepsis and septic shock are one of the most important risk factors for mortality in children. Blood cultures remain the gold standard to identify the causative organisms of sepsis and to obtain the antibiotic ... -
A retrospective analysis of the incidence of invasive candidiasis in the extreme - and very low birth weight neonates admitted to the neonatal ICU and high care unit in Universitas Academic Hospital over a 2 year period from January 2016 to December 2017 to determine if the unit will qualify for the use of fluconazole prophylaxis
(University of the Free State, 2020-06)Background: Invasive Candida infection is a leading cause of mortality and morbidity during the neonatal period, specifically in premature neonates admitted to intensive care units. Fluconazole prophylaxis has been proven ... -
Necrotising enterocolitis in the Bloemfontein academic complex
(University of the Free State, 2020-06)Background: Necrotising enterocolitis (NEC) is a serious acquired gastrointestinal emergency affecting predominantly premature neonates, especially those with a birthweight of <1500g. Despite advances in neonatal care, the ... -
The incidence of acute kidney injury amongst very low birth weight neonates in the neonatal unit at Universitas Academic Hospital during the period of January 2016 to June 2016
(University of the Free State, 2019-12)Background. Acute kidney injury is common amongst patients admitted in neonatal intensive care. It is associated with mortality and mobility especially in very low birth weight infants. We diagnose and define Acute kidney ... -
Coarctation of the Aorta: a 10-year follow-up study of patients treated at the Department of Peadiatric Cardiology, Universitas Academic Hospital
(University of the Free State, 2019-12)Background: Coarctation of the aorta accounts for 6-8% of all congenital cardiac lesions. It can be treated surgically or percutaneously depending on the age and weight at presentation and associated cardiac lesions. ... -
A retrospective analysis of the mortality, and the perinatal risk factors for mortality, of very low birth weight infants admitted to Universitas Academic Hospital over a 2-year period – January 2016 to December 2017
(University of the Free State, 2020-07)Background: A rise in preterm deliveries of very low birth weight (VLBW) infants, less than 1 500 grams, is currently introducing a global public health dilemma. VLBW infants are at increased risk for morbidity and mortality. ... -
Mortalities in the neonatal unit: after-hours compared with normal working hours at Pelonomi Tertiary Hospital over a 1-year period (January 2017 to December 2017)
(University of the Free State, 2020-04)Background: Neonatal mortality remains one of the leading causes of under-5-mortality in South Africa. South Africa has not reached the Millennium Development Goals targets for 2015 as set out by the WHO. The leading causes ... -
The disclosure of HIV status to vertically infected HIV positive children before the age of 12 years at Pelonomi Centre of Excellence
(University of the Free State, 2020-02)HIV is a chronic infection which, although cannot be cured, can be controlled with life-long treatment, provided there is good adherence. Good adherence requires a holistic approach. The patients need to have adequate food, ... -
Late onset neonatal sepsis in very low birth weight premature infants in the neonatal high care unit, Pelonomi Hospital, Bloemfontein: a cohort study
(University of the Free State, 2018)Background: Late onset neonatal sepsis (LOS) is a common problem in very low birth weight (VLBW) infants and is associated with increased mortality, morbidity and cost of care. Several known risk factors are reported in ...
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