Doctoral Degrees (Medical Physics)
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Recent Submissions
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Accuracy of lutetium-177 SPECT activity quantification and patient-specific dosimetry: a Monte Carlo study
(University of the Free State, 2021-11)The goal of radiopharmaceutical therapy (RPT) is to deliver the maximum dose to cancerous tumours while sparing healthy tissue. Ideally, the radiopharmaceutical should accumulate in the tumorous tissue and the radiation ... -
Accuracy of patient-specific dosimetry using hybrid planar-SPECT/CT imaging: a Monte Carlo study
(University of the Free State, 2021-07)Introduction: Theragnostics is a precision medical discipline aiming to individualise patient targeted treatment. It aims at treating cancer by the systemic administration of a therapeutic radiopharmaceutical, which targets ... -
Accuracy of patient-specific dosimetry using hybrid planar-SPECT/CT imaging: a Monte Carlo study
(University of the Free State, 2021-07)Introduction: Theragnostics is a precision medical discipline aiming to individualise patient targeted treatment. It aims at treating cancer by the systemic administration of a therapeutic radiopharmaceutical, which targets ... -
Accuracy of iodine-131 activity quantification and dosimetry for three-dimensional patient-specific models
(University of the Free State, 2019-03)Iodine-131 (131I) therapy of thyroid related and other diseases is limited by critical organ toxicity. Therefore, accurate activity quantification and dose calculation are important to optimise dose to tumours while limiting ... -
Segmentation and quantitative characterization of breast masses imaged using digital mammography
(University of the Free State, 2018-09)Breast cancer is the leading cause of cancer death among women. Screening Mammography is the most effective method currently available for early detection of breast cancer. When breast cancer is detected at an early stage ... -
Feasibility of tissue differentiation with multi-energy computed tomography: a Monte Carlo breast phantom study
(University of the Free State, 2017-03)English: Dedicated breast CT is a new innovative way of imaging breast tissue without the limitations of overlapping anatomical features. It has been shown that the dose received by the patient is comparable to that of ... -
Sensitivity analysis of the intergral quality monitoring system® for radiotherapy verification using Monte Carlo simulation
(University of the Free State, 2017-07)Advanced radiotherapy (RT) techniques have improved the quality of radiation treatment. Notwithstanding, advanced RT techniques have generated complexities in their quality assurance (QA). Therefore, there is a huge interest ... -
Development and evaluation of a spect attenuation correction method using an open transmission source and scatter correction
(University of the Free State, 2011-06)Abstract not available -
An equivalent uniform dose-based class solution for cervical cancer radiotherapy
(University of the Free State, 2014-06)English: Cervix cancer radiotherapy treatment consists of external beam radiotherapy (EBRT) and brachytherapy (BT). Currently there exists no method to combine the dose of both modalities in a single dose value or dose ... -
Assessment of factors affecting accuracy of standardised uptake values in positron emission tomography
(University of the Free State, 2015-01)English: Positron emission tomography (PET) is an imaging method that uses tracers labelled with positron emitting isotopes for the monitoring and evaluation of in vivo molecular processes. Semi-quantitative determination ...
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