Lung perfusion findings on perfusion SPEC T/CT imaging in non-hospitalized deisolated patients diagnosed with mild COVID-19 infection

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dc.contributor.authorEvbuomwan, Osayande
dc.contributor.authorEngelbrecht, Gerrit
dc.contributor.authorBergman, Melissa V.
dc.contributor.authorMokwena, Sello
dc.contributor.authorAyeni, Oluwatosin A.
dc.date.accessioned2022-08-22T10:53:39Z
dc.date.available2022-08-22T10:53:39Z
dc.date.issued2021
dc.description.abstractBackground: The aim of this retrospective study is to assess the incidence and type of lung perfusion abnormalities in non-hospitalized patients diagnosed with mild COVID-19 infection after de-isolation. Data from 56 non-hospitalized patients diagnosed with COVID-19 infection referred to our nuclear medicine department from July–December 2020 for a perfusion only SPECT/CT study or a ventilation perfusion SPECT/CT study were collected. Images were assessed for the presence and type of perfusion defects. The CT component of the study was also assessed for the presence of mosaic attenuation and COVID pneumonia changes. Results: Thirty-two (57.1%) cases had perfusion defects. There were 20 (35.7%) cases with defects in keeping with pulmonary embolism, 17 (30.4%) cases with defects associated with mosaic attenuation but not due to pulmonary embolism, and 6 (10.7%) of cases with defects due to pulmonary infiltrates from COVID pneumonia. A total of 24 (42.9%) cases had mosaic attenuation on CT, with 10 (17.9%) of them showing a pattern likely consistent with shunting on the perfusion images. Conclusion: Lung perfusion abnormalities are a common finding in non-hospitalized COVID-19 patients with mild disease. They are usually either due to pulmonary embolism, parenchymal infiltrates, or other causes of mosaic attenuation related to, but not specific to the pathophysiology of COVID-19 infection. The value of VQ SPECT/CT imaging is also shown in this study, in detecting and differentiating the various types of perfusion abnormalities.en_ZA
dc.description.versionPublisher's versionen_ZA
dc.identifierhttps://doi.org/10.1186/s43055-021-00521-1
dc.identifier.citationEvbuomwan, O., Engelbrecht, G., Bergman, M.V., Mokwena, S., & Ayeni, O.A. (2021). Lung perfusion findings on perfusion SPEC T/CT imaging in non-hospitalized deisolated patients diagnosed with mild COVID-19 infection. Egyptian Journal of Radiology and Nuclear Medicine, 52, 144. https://doi.org/10.1186/s43055-021-00521-1en_ZA
dc.identifier.issn2090-4762
dc.identifier.urihttp://hdl.handle.net/11660/11853
dc.language.isoenen_ZA
dc.publisherSpringerOpenen_ZA
dc.rights.holderAuthor(s)en_ZA
dc.rights.licensehttp://creativecommons.org/licenses/by/4.0/
dc.subjectVQ SPECT/CTen_ZA
dc.subjectPerfusion defectsen_ZA
dc.subjectCOVID-19en_ZA
dc.subjectPerfusion abnormalitiesen_ZA
dc.subjectMosaic attenuationen_ZA
dc.titleLung perfusion findings on perfusion SPEC T/CT imaging in non-hospitalized deisolated patients diagnosed with mild COVID-19 infectionen_ZA
dc.typeArticleen_ZA
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