Masters Degrees (Basic Medical Sciences)
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Mutational analysis of a South African haemophilia B population
(University of the Free State, 2023)Introduction and Aim: Haemophilia B is an X-linked recessive bleeding disorder characterised by a deficiency of coagulation factor IX (FIX), due to a wide spectrum of causative mutations in the FIX encoding gene (F9). Based ... -
Assessing the sexual dimorphism of the upper limb in a Free State skeletal population using univariate measurements
(University of the Free State, 2020-11)Increasing numbers of incomplete unidentified skeletal remains requiring anthropological analysis have created the need for studies of bones other than the pelvis and cranium for sex estimation purposes. This study evaluated ... -
The prevalence of anatomical variations in the intraorbital part of the ophthalmic artery and its branches in cadavers
(University of the Free State, 2017)English: The human orbit contains various important structures that may show variations relating to their anatomy. This study focused on the intraorbital part of the ophthalmic artery in a South African cadaver sample ... -
Prediction of the femoral length from markers on its proximal and distal ends
(University of the Free State, 2003-11)An estimation of stature from the whole length of limb bones is well documented. However, skeletal remains available for forensic work are often fragmentary. This study presents a prediction of the femoral length using ... -
Evaluation of a commercial radiation oncology treatment planning system against Monte Carlo simulated dose distributions
(University of the Free State, 2007-11)English: A method is described in this study whereby dose distributions calculated by a treatment planning system (TPS) were evaluated by using dose distributions calculated with Monte Carlo (MC) simulations. The MC ... -
Characterisation of ß-lactamases implicated in resistance to ß-lactem antibiotics in urinary tract infections
(University of the Free State, 2005-11-29)South Africa is not excluded from the problems encountered world-wide in the treatment of nosocomial urinary tract infections, commonly caused by enzyme-producing Enterobacteriaceae. These enzymes include the ß-lactamases ... -
Clinically relevant ex vivo fatty acid profiles from a lipid model for colorectal adenocarcinoma
(University of the Free State, 2007-11)The challenge we face today is identification of the mechanisms through which dietary factors perturb fundamental fatty acid (FA) pathways in cancer cells. In principle, insight into a lipid model for the cancer entity ... -
The effect of the embalming fluid, used by the Department of Basic Medical Sciences (UFS), on the viability of Mycobacterium TB in human cadaver lung tissue
(University of the Free State, 2012-06)Embalming fluid contains substances such as formalin, ethanol, phenol, and other solvents to prevent decomposition temporarily. These agents disinfect, preserve, and/or sanitize. The risk of contracting a disease such as ...
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