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The effect of Phela, a traditional medicine on the immune system of a rat model
(University of the Free State, 2010-08)
English: Phela is a herbal traditional medicine product prepared using well defined parts of four African medicinal plants. The aim of the study was to determine the mechanism of action by which phela boosted the immune ...
Co-morbidity of and treatment for irritable bowel syndrome, depression and anxiety in residents of retirement villages
(University of the Free State, 2014-12)
Introduction:
Irritable bowel syndrome (IBS), depression and anxiety are very common and often co-occur. Data for depression prevalence in the elderly in South Africa is available, but there is no data on the prevalence ...
Physical activity and lifestyle aspects of female students at a tertiary institution
(University of the Free State, 2013-07)
English: BACKGROUND AND RATIONALE:
It is generally believed that a sharp rise in chronic diseases and unhealthy living
has occurred. Researchers believe that the modern lifestyle and a lack in
physical activity (PA) are ...
Factors influencing antibiotic use in the paediatric intensive care unit at Universitas Hospital from 1998 to 2007
(University of the Free State, 2013-02)
English: Many antibiotics have been developed and are available on the market. An increase in the use of antibiotics in hospitals was observed and antibiotics are among the medicines most commonly prescribed to paediatric ...
Evaluation of grapefruit extract for the prevention of paracetamol-induced hepatotoxicity after overdose in rats
(University of the Free State, 2015-05)
English: Paracetamol is a widely used analgesic and antipyretic agent. While it is generally safe for use at recommended doses, acute overdose of paracetamol can cause potentially fatal liver damage. Despite the understanding ...
Cytochrome P450 and the immune response to prolonged administration of isoniazid, nevirapine and paracetamol in a rat model
(University of the Free State, 2015-02)
English: Drug-induced liver injury is a major adverse drug reaction that presents during
isoniazid (INH) and nevirapine (NVP) treatment, and after paracetamol (PAR)
overdose. It was postulated that after these drugs are ...
Development of a model to characterize the effect of Phela on selected immune markers in immune-suppressed rats
(University of the Free State, 2015-05)
The therapeutic potential of several plant species and necessity for scientific validation of the use of plant derived medicines has prompted interest in field of traditional medicines. According to the WHO, in Africa ...
Factors influencing the utilization of biological medicines in the Free State (South Africa)
(University of the Free State, 2019-06)
English: Biological Medicines are substances derived from animal or other biological origin, and are used to treat, diagnose or prevent mainly inflammatory diseases and cancer. The use thereof has grown worldwide and is ...
The effect of the traditional medicine phela on p-glycoprotein and multidrug resistance-associated protein 2 drug transporters in the gastrointestinal tract of a rat model
(University of the Free State, 2015-11)
English: Phela is the herbal preparation of four African traditional medicinal plants, and is under the development by the Medical Research Council (MRC) as an immune stimulant for immune compromised individuals. Patients ...