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Transfusion practices in the Eastern Cape Province of South Africa in the era of HIV and HAART
(University of the Free State, 2014)
The HIV/AIDS pandemic has irrevocably changed the face of healthcare delivery and research. This is especially true in South Africa with its estimated 5.26 million HIV-infected people. It was not until the significant up ...
Necrotising migratory erythema leading to the diagnosis of a metastatic glucagonoma without diabetes
(University of the Free State, 2020-08)
A case of necrotising migratory erythema (NME), which is one of the distinctive paraneoplastic skin manifestations associated with the glucagonoma syndrome, is described and discussed. In 80% of all patients with glucagonoma, ...
Diagnostic accuracy of ultrasound-guided fine needle aspiration cytology of thyroid nodules at Universitas Academic Hospital, Bloemfontein
(University of the Free State, 2020-06)
Background: Fine Needle Aspiration Cytology (FNAC), is safe, reliable and minimally invasive first-line investigation used to evaluate thyroid nodules. Aim: To determine the diagnostic accuracy of FNAC performed at our ...
The prevalence of polypharmacy and prescription of potentially inappropriate medications in the elderly
(University of the Free State, 2021-03)
Background: The proportion of the elderly population, considered to be the main consumers of medicine, is on the increase. High multimorbidity prevalence in elderly increases the risk for appropriate- and inappropriate ...
Assessing adherence to recommended HIV Post Exposure Prophylaxis regimens prescribed to doctors working at the Free State Academic Complex in Bloemfontein, South Africa
(University of the Free State, 2021-05)
Background: The prevalence of HIV infection in South Africa is one of the highest in the world and healthcare workers in this setting are particularly at risk of being infected through occupational exposures. All high-risk ...
National profile of the characteristics of patients treated for TTP an extension of the study: the characteristics of patients with TTP at the Universitas Haematology Department from 2010-2017 (HSD2018/0114)
(University of the Free State, 2021)
Thrombotic thrombocytopenic purpura (TTP) is a rare life-threatening haematological disorder. It is caused by a deficiency in ADAMTS13. ADAMTS13 is a zinc-containing
Metalloprotease enzyme that cleaves Von Willebrand ...
Drug interactions between HIV-associated lymphoma treatment and antiretroviral therapy
(University of the Free State, 2019-11)
Despite the large-scale roll-out of ART in the mid-1990s, HIV and HIV-associated diseases remain a major health problem in South Africa. HIV-associated lymphoma contributes significantly to the morbidity and mortality of ...
Dyslipidaemia pattern and prevalence among type 2 diabetes mellitus patients on lipid-lowering therapy at a Tertiary Central South African Hospital
(University of the Free State, 2020-09)
Background: Atherosclerotic cardiovascular disease (ASCVD) is a major cause of death worldwide. A large number of deaths due to ASCVD occur among people with diabetes mellitus (DM). One of the important modifiable risk ...