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Laboratory diagnosis and management of von Willebrand disease in South Africa

Meiring, Muriel; Coetzee, Marius; Kelderman, Mareli; Badenhorst, Philip (Thieme Medical Publishers, 2011)

Patients with von Willebrand disease (VWD) in South Africa are cared for in 17 Hemophilia Treatment Centers. The exact prevalence of the disease is uncertain, but 539 patients are annotated in registries. VWD patients ...

Phase I, randomized, double-blind, placebo-controlled, single-dose escalation study of the recombinant factor VIIa variant BAY 86-6150 in hemophilia

Mahlangu, J. N.; Coetzee, M. J.; Laffan, M.; Windyga, J.; Yee, T. T.; Schroeder, J.; Haaning, J.; Siegel, J. E.; Lemm, G. (International Society on Thrombosis and Haemostasis, 2012)

Background: BAY 86-6150 is a new human recombinant factor VIIa variant developed for high procoagulant activity and longer action in people with hemophilia with inhibitors. Objectives: To investigate the safety, ...