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    Molecular screening of Coloured South African breast cancer patients for the presence of BRCA mutations using high resolution melting analysis 

    Oosthuizen, Jaco (University of the Free State, 2016-08)
    English: The populations of South Africa (SA) exhibit a rainbow of genetic diversity due to the high contribution of ancestral genetic admixture. The economic structure of this third world country has limited the exploration ...
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    Molecular screening for the presence of large deletions or duplications in BRCA using Multiplex ligation-dependent probe amplification in South Africa 

    Moeti, Pakiso James (University of the Free State, 2016-07)
    English: Germline BRCA gene mutations are associated with hereditary breast and ovarian cancers (OVC). Identification of these mutations greatly improves the preventive strategies and management of patients affected with ...
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    Molecular screening of the South African Indian population for BRCA1 and BRCA2 using high resolution melting analysis 

    Combrink, H. M. V. E. (University of the Free State, 2016-01)
    English: The lifetime risk for developing breast cancer within the Indian population of South Africa is one in 17. Disease causing mutations in BRCA1/2 increase the risk of developing this disease by up to 80%. The main ...

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    AuthorCombrink, H. M. V. E. (1)Moeti, Pakiso James (1)Oosthuizen, Jaco (1)Subject
    Breast -- Cancer -- Genetic aspects (3)
    Dissertation (M.Med.Sc. (Human Genetics))--University of the Free State, 2016 (3)BRCA1/2 (2)Breast -- Cancer (2)HRMA (2)South Africa (2)BRCA1 (1)BRCA2 (1)Coloured population (1)Computer-based analysis (1)... View MoreDate Issued2016 (3)Has File(s)
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