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Sequensing of exon 28 of Von Willebrand factor in five patients with type 2 Von Willebrand disease
(University of the Free State, 2009-05)
English: Von Willebrand disease (VWD) is a common bleeding disorder caused by either quantitative (type1 and 3) or qualitative (type 2) defects of von Willebrand factor (VWF). The diagnosis of VWD usually requires a panel ...
The evaluation of tirofiban hydrochloride in a high shear rate arterial thrombosis model in baboons
(University of the Free State, 2009-11)
English: Background: Acute coronary syndrome (ACS) is a major cause of mortality and morbidity
world-wide, and is responsible for roughly 2.5 million hospital admissions world-wide annually.
ACS is commonly associated ...
The screening for single nucleotide polymorphisms of CYP3A4 in chronic myelogenous leukemia patients receiving imatinib
(University of the Free State, 2009-05)
English: Chronic myelogenous leukaemia (CML) is a malignant clonal disorder that results in the uncontrolled production of white blood cells. This disease is a result of a reciprocal translocation of the long arms of ...