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Co-expression and functional assay of human Rb and E2F1 proteins in yeast
(University of the Free State, 1999-09)
The mammalian cell cycle is composed of a myriad interactions occurring in a defined
sequence dictated by the flow of entropy. The decision to study the cell cycle requires
entry into a world where events take place, not ...
A yeast-based assay for detection of mutations in the human p16 gene
(University of the Free State, 1999-05)
Cyclin-dependent kinases (CDKs) are crucial regulators of the cell cyele. CDKs
themselves are subject to control by both cyelins and CDK inhibitors. Among the
inhibitors, p 16 is very prominent, since it has been found ...