Van Aswegen, A.De Bruyn, Martha Magdalena2019-12-042019-12-042019-06http://hdl.handle.net/11660/10356Tumours of the central nervous system are a common and challenging entity seen by Neurosurgery Departments worldwide. It is the cause of significant morbidity and mortality worldwide. Since the advent of Neurosurgery there has been an immense interest in classifying these tumours to enable prognostication and optimize the management of these tumours. Various classification systems have been used with the latest being the 2016 WHO classification of tumours of the central nervous system. The discovery of the molecular and genetic basis of these tumours and the development of these characteristics to aid in the diagnosis and management of these tumours, have had a great impact on the classification of these tumours. In developed countries, tumour registries exist to optimize the diagnosis and management of these tumours and to identify fields of possible further research and development. There is a lack of such registries in most developing countries and the need exist to establish such registries. The aim of this study is to implement a central nervous system tumour registry at the Universitas Academic Hospital in Bloemfontein to assist with the diagnosis, management and further resource implementation to optimize our management of these tumours and to enable us to compare our data with the international and national data bases.enDissertation (M.Med (Neurosurgery))--University of the Free State, 20192016 WHO classification of tumours of the central nervous systemSupratentorialHistologyMolecularGeneticInfratentorialBiopsyDebulkingResectionMalignant/high grade/anaplasticLow gradeDissertationUniversity of the Free State