Now showing items 1-2 of 2
The role of the immune system in nevirapine induced hepatotoxicity in a rat model
(University of the Free State, 2010)
English: Nevirapine is associated with hypersensitivity reactions such as skin rash and hepatotoxicity, hampering its use for HIV prophylaxis. The mechanism of nevirapine induced hepatotoxicity remains unknown and was ...
Cytochrome P450 and the immune response to prolonged administration of isoniazid, nevirapine and paracetamol in a rat model
(University of the Free State, 2015-02)
English: Drug-induced liver injury is a major adverse drug reaction that presents during isoniazid (INH) and nevirapine (NVP) treatment, and after paracetamol (PAR) overdose. It was postulated that after these drugs are ...