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Cryptococcal protease(s) and the activation of SARS-CoV-2 spike (S) protein
(MDPI, 2022)
In this contribution, we report on the possibility that cryptococcal protease(s) could activate
the SARS-CoV-2 spike (S) protein. The S protein is documented to have a unique four-amino-acid
sequence (underlined, SPRRAR|S) ...
The repurposing of acetylsalicylic acid as a photosensitiser to inactivate the growth of cryptococcal cells
(MDPI, 2021)
Photodynamic treatment (PDT) is often successful when used against aerobic microbes, given their natural susceptibility to oxidative damage. To this end, the current study aimed to explore the photodynamic action of ...
Recent advances and opportunities in the study of Candida albicans polymicrobial biofilms
(Frontiers, 2022)
It is well known that the opportunistic pathogenic yeast, Candida albicans, can form polymicrobial biofilms with a variety of bacteria, both in vitro and in vivo, and that these polymicrobial biofilms can impact the course ...
Risk factors for fungal co-infections in critically ill COVID-19 patients, with a focus on immunosuppressants
(MDPI, 2021)
Severe cases of coronavirus disease 2019 (COVID-19) managed in the intensive care unit are prone to complications, including secondary infections with opportunistic fungal pathogens. Systemic fungal co-infections in ...
Rotavirus-mediated prostaglandin E2 production in MA104 cells promotes virus attachment and internalisation, resulting in an increased viral load
(Frontiers Media, 2022)
Rotaviruses are one of the leading causes of severe dehydrating diarrhoea in infants and children under the age of five. Despite the introduction of vaccines, disease burden remains high in sub-Saharan Africa, with no known ...
Candida albicans-enteric viral interactions—the prostaglandin E2 connection and host immune responses
(Cell Press, 2023)
The human microbiome comprises trillions of microorganisms residing within different mucosal cavities and across the body surface. The gut microbiota modulates host susceptibility to viral infections in several ways, and ...
Candida albicans-enteric viral interactions—the prostaglandin E2 connection and host immune responses
(Cell Press, 2023)
The human microbiome comprises trillions of microorganisms residing within different mucosal cavities and across the body surface. The gut microbiota modulates host susceptibility to viral infections in several ways, and ...