Now showing items 1-10 of 12
Identification of antigen-specific serological cross-reactivity among survivors of Crimean-Congo Haemorrhagic fever
(University of the Free State, 2013)
Abstract not available
Immune responses to Crimean-Congo haemorrhagic fever virus and molecular characterization of viral isolates
(University of the Free State, 2014-02)
Crimean-Congo haemorrhagic fever virus (CCHFV) is a tick-borne virus belonging to the family Bunyaviridae, genus Nairovirus. The distribution of the virus correlates with that of the principal vector, ticks belonging to ...
Identification of antigenic regions and linear B cell epitopes on yellow fever virus
(University of the Free State, 2013-02)
English: Yellow fever virus (YFV) virus is an arthropod-borne virus that causes viral hemorrhagic fever in humans in the tropical parts of both Africa and South America. The virus belongs to the family Flaviviridae, of the ...
Preparation of recombinant antigens for demonstrating antibody responses in patients with Crimean-Congo haemorrhagic fever virus infections
(University of the Free State, 2011-06)
Crimean-Congo haemorrhagic fever (CCHF) is a tick-borne viral zoonosis widely distributed in Africa, Asia, Russia and the Balkans. The causative agent, CCHF virus (CCHFV) has the propensity to cause nosocomial infections ...
Development of detection assays for sindbus virus and investigating in vitro infection of mammalian cells
(University of the Free State, 2013-08)
Sindbis virus (SINV) is a member of the Alphavirus genus and belongs to the family Togaviridae. The virus has a positive sense RNA genome of 11700 bases which encodes for both structural and non structural proteins. ...
Preparation and immunogenicity of a candidate replicon based yellow fever vaccine
(University of the Free State, 2014-12)
English: Yellow fever virus (YFV), a mosquito-borne virus that belongs to the family Flaviviridae and genus Flavivirus, is a significant cause of morbidity and mortality in yellow fever endemic areas, especially in West ...
Development of molecular and serological assays for diagnosis and surveillance of Crimean-Congo haemorrhagic fever virus
(University of the Free State, 2015-05)
Crimean-Congo haemorrhagic fever virus (CCHFV) an arthropod-borne virus associated with haemorrhagic disease in humans. The global distribution of CCHFV correlates with that of ticks from the Hyalomma genus. CCHFV infection ...
Preparation of recombinant antigen for serological detection of African hantaviruses
(University of the Free State, 2017-07)
Unlike other members of the Bunyaviridae family, hantaviruses are transmitted to humans through direct exposure or inhalation of virus contaminated urine or droppings from their reservoir hosts. Hantaviruses were first ...
Immunogenicity and serological applications of flavivirus ED III proteins and multiplex RT-PCR for detecting novel Southern African viruses
(University of the Free State, 2015-01)
English: West Nile virus (WNV) is endemic to southern Africa but the true burden of disease associated with WNV infection remains unknown in this region. The presence of the mosquito-borne Wesselsbron virus (WESSV) has ...