• Login
    Search 
    •   KovsieScholar Home
    • Health Sciences
    • Haematology and Cell Biology
    • Masters Degrees (Haematology and Cell Biology)
    • Search
    •   KovsieScholar Home
    • Health Sciences
    • Haematology and Cell Biology
    • Masters Degrees (Haematology and Cell Biology)
    • Search
    JavaScript is disabled for your browser. Some features of this site may not work without it.

    Search

    Show Advanced FiltersHide Advanced Filters

    Filters

    Use filters to refine the search results.

    Now showing items 1-10 of 15

    • Sort Options:
    • Relevance
    • Title Asc
    • Title Desc
    • Issue Date Asc
    • Issue Date Desc
    • Results Per Page:
    • 5
    • 10
    • 20
    • 40
    • 60
    • 80
    • 100
    Thumbnail

    Genotypic and expression analysis of CYP3A4 and CYP3A5 in patients with chronic myeloid leukaemia 

    Thompson, Gaynor Gillian (University of the Free State, 2013-01)
    Chronic myeloid leukaemia (CML) is a haematological malignancy characterised by the BCR-ABL fusion oncogene which encodes for a constitutively active tyrosine kinase. Imatinib mesylate is a tyrosine kinase inhibitor that ...
    Thumbnail

    The application of high-resolution melting curve analysis for the detection of mutations in the MCR-ABL kinase domain of patients with chronic myeloid leukaemia 

    Wienand, Kirsty (University of the Free State, 2011-12)
    CML is a haematological malignancy that is characterized by the BCR-ABL fusion oncogene that encodes a constitutively active tyrosine kinase. The treatment of choice for CML is a tyrosine kinase inhibitor and molecular ...
    Thumbnail

    Molecular screening of Coloured South African breast cancer patients for the presence of BRCA mutations using high resolution melting analysis 

    Oosthuizen, Jaco (University of the Free State, 2016-08)
    English: The populations of South Africa (SA) exhibit a rainbow of genetic diversity due to the high contribution of ancestral genetic admixture. The economic structure of this third world country has limited the exploration ...
    Thumbnail

    Characterization of a human inhibitory antibody fragment against tissue factor 

    Vermeulen, Jan-G. (University of the Free State, 2011-11)
    English: Tissue factor is a transmembrane glycoprotein that functions as the primary initiator of coagulation in response to mechanical or chemical damage. Due to its key position within the coagulation cascade it also ...
    Thumbnail

    Molecular screening for the presence of large deletions or duplications in BRCA using Multiplex ligation-dependent probe amplification in South Africa 

    Moeti, Pakiso James (University of the Free State, 2016-07)
    English: Germline BRCA gene mutations are associated with hereditary breast and ovarian cancers (OVC). Identification of these mutations greatly improves the preventive strategies and management of patients affected with ...
    Thumbnail

    Presence of glyphosate in food products in South Africa of which maize or soybean is the primary constituent 

    Koortzen, B. J. (University of the Free State, 2017-02)
    English: South Africa is considered a major GM crop producing country. The predominant GM trait in maize and soybean in South Africa is herbicide tolerance. Herbicide tolerant (HT) crops allow for the application of herbicide ...
    Thumbnail

    Mutational analysis of the Janus Kinase 2 gene in patients with polycythaemia vera, essential thrombocythaemia and primary myelofibrosis 

    Goodyear, Quintin Clive (University of the Free State, 2011-11)
    All the cells of blood arise from two lineages, the myeloid and the lymphoid lineage. The various cells of blood perform vital functions in the body. These cell counts are closely regulated by regulatory pathways. Mutations ...
    Thumbnail

    Microparticles derived from stimulation of human umbilical endothelium 

    Le Roux, Elzette (University of the Free State, 2013)
    English: Endothelial microparticle reseach is currently a very novel and exciting topic in the field of haemosistasis and thrombosis. The role of microparticles in inflammatory and thrombotic disorders is however not ...
    Thumbnail

    The effect of inflammatory cytokines and coagulation factors on Von Willebrand factor synthesis and cleavage 

    Allers, Werner Ernst (University of the Free State, 2012-02)
    When injured, endothelial cells secrete inflammatory cytokines such as interleukin-6 (IL-6), interleukin-8 (IL-8), and tumour necrosis factor-α (TNF-α). These inflammatory cytokines stimulate the endothelial release of ...
    Thumbnail

    Molecular screening of the South African Indian population for BRCA1 and BRCA2 using high resolution melting analysis 

    Combrink, H. M. V. E. (University of the Free State, 2016-01)
    English: The lifetime risk for developing breast cancer within the Indian population of South Africa is one in 17. Disease causing mutations in BRCA1/2 increase the risk of developing this disease by up to 80%. The main ...
    • 1
    • 2

    DSpace software copyright © 2002-2016  DuraSpace
    Contact Us | Send Feedback
     

     

    Browse

    All of KovsieScholarCommunities & CollectionsBy Issue DateAuthorsTitlesSubjectsThis CollectionBy Issue DateAuthorsTitlesSubjects

    My Account

    LoginRegister

    Discover

    AuthorAllers, Werner Ernst (1)Combrink, H. M. V. E. (1)Du Toit, Egardt (1)Goodyear, Quintin Clive (1)Khemisi, Mmakgabu Martha (1)Koortzen, B. J. (1)Le Roux, Elzette (1)Moeti, Pakiso James (1)Nienaber, Elzette (1)Oosthuizen, Jaco (1)... View MoreSubjectBlood -- Coagulation (3)Breast -- Cancer -- Genetic aspects (3)Dissertation (M.Med.Sc. (Human Genetics))--University of the Free State, 2016 (3)South Africa (3)BRCA1/2 (2)Breast -- Cancer (2)Cytokines (2)Dissertation (M.Med.Sc. (Haematology and Cell Biology))--University of the Free State, 2013 (2)HRMA (2)Inflammation -- Treatment (2)... View MoreDate Issued2016 (5)2011 (3)2013 (2)2012 (1)2014 (1)2015 (1)2017 (1)2018 (1)Has File(s)
    Yes (15)

    DSpace software copyright © 2002-2016  DuraSpace
    Contact Us | Send Feedback