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Molecular screening of Coloured South African breast cancer patients for the presence of BRCA mutations using high resolution melting analysis
(University of the Free State, 2016-08)
English: The populations of South Africa (SA) exhibit a rainbow of genetic diversity due to the high contribution of ancestral genetic admixture. The economic structure of this third world country has limited the exploration ...
Molecular screening for the presence of large deletions or duplications in BRCA using Multiplex ligation-dependent probe amplification in South Africa
(University of the Free State, 2016-07)
English: Germline BRCA gene mutations are associated with hereditary breast and ovarian cancers (OVC). Identification of these mutations greatly improves the preventive strategies and management of patients affected with ...