Now showing items 1-2 of 2
Microparticles derived from stimulation of human umbilical endothelium
(University of the Free State, 2013)
English: Endothelial microparticle reseach is currently a very novel and exciting topic in the field of haemosistasis and thrombosis. The role of microparticles in inflammatory and thrombotic disorders is however not ...
Genotypic and expression analysis of CYP3A4 and CYP3A5 in patients with chronic myeloid leukaemia
(University of the Free State, 2013-01)
Chronic myeloid leukaemia (CML) is a haematological malignancy characterised by the BCR-ABL fusion oncogene which encodes for a constitutively active tyrosine kinase. Imatinib mesylate is a tyrosine kinase inhibitor that ...